Design and synthesis of novel 6,7-imidazotetrahydroquinoline inhibitors of thymidylate synthase using iterative protein crystal structure analysisREICH, S. H; FUHRY, M. A. M; BARTLETT, C. A et al.Journal of medicinal chemistry (Print). 1992, Vol 35, Num 5, pp 847-858, issn 0022-2623Article

Photo-CIDNP and nanosecond laser flash photolysis studies on the photodecomposition of triarylsulfonium saltsWELSH, K. M; DEKTAR, J. L; GARCIA-GARIBAYA, M. A et al.Journal of organic chemistry. 1992, Vol 57, Num 15, pp 4179-4184, issn 0022-3263Article

Separation of cis and trans isomers of 1,4-disilacyclohexadienes and related 9,10-dihydro-9,10-disilaanthracenesWELSH, K. M; COREY, J. Y.Organometallics. 1987, Vol 6, Num 7, pp 1393-1398, issn 0276-7333Conference Paper

Synthesis and biological evaluation of novel 2,6-diaminobenz[cd]indole inhibitors of thymidylate synthase using the protein structure as a guideVARNEY, M. D; PALMER, C. L; DEAL, J. G et al.Journal of medicinal chemistry (Print). 1995, Vol 38, Num 11, pp 1892-1903, issn 0022-2623Article

Design of enzyme inhibitors using iterative protein crystallographic analysisAPPELT, K; BACQUET, R. J; JONES, T. R et al.Journal of medicinal chemistry (Print). 1991, Vol 34, Num 7, pp 1925-1934, issn 0022-2623Article

Dynamics of interaction between a 1,9-biradical and lanthanide ionsWANG, J; WELSH, K. M; WATERMAN, K. C et al.Journal of physical chemistry (1952). 1988, Vol 92, Num 13, pp 3730-3732, issn 0022-3654Article

Evidence that catalysis by yeast inorganic pyrophosphatase proceeds by direct phosphoryl transfer to water and not via a phosphoryl enzyme intermediateGONZALEZ, M. A; WEBB, M. R; WELSH, K. M et al.Biochemistry (Easton). 1984, Vol 23, Num 5, pp 797-801, issn 0006-2960Article

Calculation of solvation and binding free energy differences for folate-based inhibitors of the enzyme thymidylate synthaseRAMI REDDY, M; BACQUET, R. J; ZICHI, D et al.Journal of the American Chemical Society. 1992, Vol 114, Num 26, pp 10117-10122, issn 0002-7863Article

Alteration of the metastatic potential of line 1 lung carcinoma cells : opposite effects of class I antigen induction by interferons versus DMSO or gene transfectionCEROSALETTI, K. M; BLIEDEN, T. M; HARWELL, L. W et al.Cellular immunology (Print). 1990, Vol 127, Num 2, pp 299-310, issn 0008-8749, 12 p.Article

Isolation and characterization of the Escherichia coli mutL gene productGRILLEY, M; WELSH, K. M; SHIN-SAN SU et al.The Journal of biological chemistry (Print). 1989, Vol 264, Num 2, pp 1000-1004, issn 0021-9258Article

Chemically induced dynamic nuclear polarization in systems containing large hyperfine coupling constantsROTH, H. D; HUTTON, R. S; KUO-CHU HWANG et al.Journal of physical chemistry (1952). 1989, Vol 93, Num 15, pp 5697-5701, issn 0022-3654, 5 p.Article

Isolation and characterization of the Escherichia coli mutH gene productWELSH, K. M; A-LIEN LU; CLARK, S et al.The Journal of biological chemistry (Print). 1987, Vol 262, Num 32, pp 15624-15629, issn 0021-9258Article

Yeast inorganic pyrophosphatase. A model for active-site structure based on ¹¹³Cd²⁺ and ³¹P NMR studiesWELSH, K. M; COOPERMAN, B. S.Biochemistry (Easton). 1984, Vol 23, Num 21, pp 4947-4955, issn 0006-2960Article

Restrictive dermopathy : report of two affected siblings and a review of the literatureWELSH, K. M; SMOLLER, B. R; HOLBROOK, K. A et al.Archives of dermatology (1960). 1992, Vol 128, Num 2, pp 228-231, issn 0003-987XArticle

Photochemistry of triphenylsulfonium salts in poly[4-tert-butoxycarbonyl-oxy]styrene] : evidence for a dual photoinitiation processHACKER, N. P; WELSH, K. M.Macromolecules. 1991, Vol 24, Num 8, pp 2138-2139, issn 0024-9297, 2 p.Article

The effect of recombinant human growth hormone on wound healing in normal individualsWELSH, K. M; LAMIT, M; MORHENN, V. B et al.The Journal of dermatologic surgery and oncology. 1991, Vol 17, Num 12, pp 942-945, issn 0148-0812Article

Photochemistry of a matrix-isolated geminal diazide. DimethylgermyleneBARRAU, J; BEAN, D. L; WELSH, K. M et al.Organometallics. 1989, Vol 8, Num 11, pp 2606-2608, issn 0276-7333Article

Matrix isolation of the first silanediimine, N,N'-bis(trimethylsilyl)silanediimineZIGLER, S. S; WELSH, K. M; WEST, R et al.Journal of the American Chemical Society. 1987, Vol 109, Num 14, pp 4392-4393, issn 0002-7863Article

The generation of hexamethyl-1,4-disilabenzene and its novel thermal chemistryWELSH, K. M; RICH, J. D; WEST, R et al.Journal of organometallic chemistry. 1987, Vol 325, Num 1-2, pp 105-115, issn 0022-328XArticle

Structure-based design of substituted diphenyl sulfones and sulfoxides as lipophilic inhibitors of thymidylate synthaseJONES, T. R; WEBBER, S. E; WEBBER, S et al.Journal of medicinal chemistry (Print). 1997, Vol 40, Num 5, pp 677-683, issn 0022-2623Article

Structure-based design of lipophilic quinazoline inhibitors of thymidylate synthaseJONES, T. R; VARNEY, M. D; APPELT, K et al.Journal of medicinal chemistry (Print). 1995, Vol 39, Num 4, pp 904-917, issn 0022-2623Article

Design of thymidylate synthase inhibitors using protein crystal structures : the synthesis and biological evaluation of a novel class of 5-substituted quinazolinonesWEBBER, S. E; BLECKMAN, T. M; FREER, S. T et al.Journal of medicinal chemistry (Print). 1993, Vol 36, Num 6, pp 733-746, issn 0022-2623Article

Crystal-structure-based design and synthesis of benz[cd]indole-containing inhibitors of thymidylate synthaseVARNEY, M. D; MARZONI, G. P; HERRMANN, S. M et al.Journal of medicinal chemistry (Print). 1992, Vol 35, Num 4, pp 663-676, issn 0022-2623Article

Enhancement or suppression of CIDNP intensities by a second magnetic nucleus : interplay between g factor difference, external magnetic field, and hyperfine coupling constantsKUO CHU HWANG; ROTH, H. D; TURRO, N. J et al.Journal of physical organic chemistry. 1992, Vol 5, Num 4, pp 209-217, issn 0894-3230Article

The photochemistry of matrix-isolated di-tert-butyldiazidosilane. Observation of di-tert-butylsilylene and N,N'-di-tert-butylsilanediimineWELSH, K. M; MICHL, J; WEST, R et al.Journal of the American Chemical Society. 1988, Vol 110, Num 20, pp 6689-6696, issn 0002-7863Article